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1

The cytoplasm of living cells behaves as a poroelastic material

Moeendarbary, Emad, Valon, Léo, Fritzsche, Marco, Harris, Andrew R., Moulding, Dale A., Thrasher, Adrian J., Stride, Eleanor, Mahadevan, L., Charras, Guillaume T.

Journal:

Nature Materials

Year:

2013

Language:

english

File:

PDF, 977 KB

english, 2013

2

455. Automated Lentiviral Transduction of T Cells with CARS Using the CliniMACS Prodigy

Nickolay, Lauren, Mock, Ulrike, Phillip, Brian, Cheung, Gordon Weng Kit, Zhan, Hong, Peggs, Karl, Johnston, Ian, Kaiser, Andrew, Pule, Martin, Thrasher, Adrian, Qasim, Waseem

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 341 KB

english, 2016

3

WASP: a key immunological multitasker

Thrasher, Adrian J., Burns, Siobhan O.

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 470 KB

english, 2010

4

Treating Immunodeficiency through HSC Gene Therapy

Booth, Claire, Gaspar, H. Bobby, Thrasher, Adrian J.

Journal:

Trends in Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

5

Gene therapy: progress and predictions

Collins, Mary, Thrasher, Adrian

Journal:

Proceedings Biological Sciences

Year:

2015

Language:

english

File:

PDF, 547 KB

english, 2015

6

Bleeding and splenectomy in Wiskott-Aldrich syndrome: A single-centre experience

Rivers, Elizabeth, Worth, Austen, Thrasher, Adrian J., Burns, Siobhan O.

Journal:

The Journal of Allergy and Clinical Immunology: In Practice

Year:

2018

Language:

english

File:

PDF, 148 KB

english, 2018

7

One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years

Elfeky, Reem Ahmed, Furtado-Silva, Juliana M., Chiesa, Robert, Rao, Kanchan, Amrolia, Persis, Lucchini, Giovanna, Gilmour, Kimberly, Adams, Stuart, Bibi, Shahnaz, Worth, Austen, Thrasher, Adrian J., Q

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 885 KB

english, 2018

8

Wiskott-Aldrich syndrome: a disorder of haematopoietic cytoskeletal regulation

Thrasher, Adrian J., Burns, Siobhan

Journal:

Microscopy Research and Technique

Year:

1999

Language:

english

File:

PDF, 192 KB

english, 1999

9

Detailed characterization of the human aorta-gonad-mesonephros region reveals morphological polarity resembling a hematopoietic stromal layer

Caroline J. Marshall, Rachel L. Moore, Peter Thorogood, Paul M. Brickell, Christine Kinnon, Adrian J. Thrasher

Journal:

Developmental Dynamics

Year:

1999

Language:

english

File:

PDF, 727 KB

english, 1999

10

Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome

Michael Binks, Gareth E. Jones, Paul M. Brickell, Christine Kinnon, David R. Katz, Adrian J. Thrasher

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 150 KB

english, 1998

11

Intrinsic defects of B cell function in X-linked severe combined immunodeficiency

Harry White, Adrian Thrasher, Paul Veys, Christine Kinnon, Hubert B. Gaspar

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

12

Diagnosis of X-linked lymphoproliferative disease by analysis of SLAM-associated protein expression

Kimberly C. Gilmour, Treena Cranston, Alison Jones, E. Graham Davies, David Goldblatt, Adrian Thrasher, Christine Kinnon, Kim E. Nichols, Hubert B. Gaspar

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

13

Maturation of DC is associated with changes in motile characteristics and adherence

Siobhan Burns, Samantha J. Hardy, Joanna Buddle, Kwee L. Yong, Gareth E. Jones, Adrian J. Thrasher

Journal:

Year:

2004

Language:

english

File:

PDF, 661 KB

english, 2004

14

Lentivectors are efficient tools to manipulate the dendritic cell cytoskeleton

Joao Metelo, Natalie Ward, Adrian J. Thrasher, Siobhan O. Burns

Journal:

Year:

2011

Language:

english

File:

PDF, 970 KB

english, 2011

15

Long-term evaluation of retinal function in Prph2Rd2/Rd2 mice following AAV-mediated gene replacement therapy

Frank C. Schlichtenbrede, Lyndon da Cruz, Clare Stephens, Alexander J. Smith, Anastasios Georgiadis, Adrian J. Thrasher, James W. B. Bainbridge, Mathias W. Seeliger, Robin R. Ali

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 306 KB

english, 2003

16

Enhancer-deleted retroviral vectors restore high levels of superoxide generation in a mouse model of CGD

Oliver Schwickerath, Gaby Brouns, Adrian Thrasher, Christine Kinnon, Jürgen Roes, Colin Casimir

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 418 KB

english, 2004

17

Is Wiskott–Aldrich syndrome a cell trafficking disorder?

Adrian J Thrasher, Gareth E Jones, Christine Kinnon, Paul M Brickell, David R Katz

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 144 KB

english, 1998

18

The Wiskott–Aldrich syndrome: disordered actin dynamics in haematopoietic cells

Adrian J. Thrasher, Siobhan Burns, Roberto Lorenzi, Gareth E. Jones

Journal:

Immunological Reviews

Year:

2000

Language:

english

File:

PDF, 5.81 MB

english, 2000

19

WISKOTT-ALDRICH SYNDROME: CURRENT RESEARCH CONCEPTS

Paul M. Brickell, David R. Katz, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 625 KB

english, 1998

20

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor γ chain

Jacki P Goldman, Michael P Blundell, Lucien Lopes, Christine Kinnon, James P DI Santo, Adrian J Thrasher

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 1.15 MB

english, 1998

21

The embryonic origins of human haematopoiesis

Caroline J. Marshall, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 386 KB

english, 2001

22

Protein assays for diagnosis of Wiskott–Aldrich syndrome and X-linked thrombocytopenia

Waseem Qasim, Kimberly C. Gilmour, Stephanie Heath, Eleanor Ashton, Treena Cranston, Angela Thomas, Adam Finn, E. Graham Davies, Adrian J. Thrasher, Christine Kinnon, Alison Jones, Hubert B. Gaspar

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

23

X-linked lymphoproliferative disease: clinical, diagnostic and molecular perspective

Hubert B. Gaspar, Reza Sharifi, Kimberly C. Gilmour, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

24

The impact of retroviral suicide gene transduction procedures on T cells

Waseem Qasim, Douglas King, Jo Buddle, Stephanie Verfuerth, Christine Kinnon, Adrian J. Thrasher, Hubert B. Gaspar

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 516 KB

english, 2003

25

Wiskott–Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

Yolanda Calle, Hsiu-chuan Chou, Adrian J Thrasher, Gareth E Jones

Journal:

The Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 346 KB

english, 2004

26

Development of anti-PAX3 immune responses; a target for cancer immunotherapy

Nourredine Himoudi, Steven Nabarro, Mengyong Yan, Kimberly Gilmour, Adrian J. Thrasher, John Anderson

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 526 KB

english, 2007

27

In vivo myocardial gene transfer: Optimization, evaluation and direct comparison of gene transfer vectors

Matt J. Wright, Lionel M. L. Wightman, Caroline Lilley, Mahesh de Alwis, Steven L. Hart, Andrew Miller, Robert S. Coffin, Adrian Thrasher, David S. Latchman, Michael S. Marber

Journal:

Basic Research in Cardiology

Year:

2001

Language:

english

File:

PDF, 541 KB

english, 2001

28

Sequence Analysis ofTNFRSF13b, Encoding TACI, in Patients with Systemic Lupus Erythematosus

Ulrich Salzer, Jennifer Birmelin, Chiara Bacchelli, Torsten Witte, Ulrike Buchegger-Podbielski, Sylvie Buckridge, Rita Rzepka, H. Bobby Gaspar, Adrian J. Thrasher, Reinhold E. Schmidt, Inga Melchers,

Journal:

Journal of Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 281 KB

english, 2007

29

Severe cutaneous papillomavirus disease after haematopoietic stem-cell transplantation in patients with severe combined immunodeficiency

H. Bobby Gaspar, Catherine Harwood, Irene Leigh, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

30

Autoimmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype

Austen Worth, Adrian J. Thrasher, H. Bobby Gaspar

Journal:

British Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

31

CD34+ stem cell top-ups without conditioning after initial haematopoietic stem cell transplantation for correction of incomplete haematopoietic and immunological recovery in severe congenital immunodeficiencies

Claire Booth, Jean-Antoine Ribeil, Françoise Audat, Liliane Dal-Cortivo, Paul A Veys, Adrian J Thrasher, E. Graham Davies, François Lefrère, Alain Fischer, Marina Cavazzana-Calvo, H. Bobby Gaspar

Journal:

British Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 72 KB

english, 2006

32

Bone morphogenetic protein 4 modulates c-Kit expression and differentiation potential in murine embryonic aorta-gonad-mesonephros haematopoiesis in vitro

Caroline J. Marshall, Joanna C. Sinclair, Adrian J. Thrasher, Christine Kinnon

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 502 KB

english, 2007

33

Repeated courses of rituximab for autoimmune cytopenias may precipitate profound hypogammaglobulinaemia requiring replacement intravenous immunoglobulin

Nichola Cooper, E. Graham Davies, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 130 KB

english, 2009

34

Impaired neutrophil migration and phagocytosis in IRAK-4 deficiency

Gerben Bouma, Rainer Doffinger, Smita Y. Patel, Emma Peskett, Joanna C. Sinclair, Gabriela Barcenas-Morales, Lourdes Cerron-Gutierrez, Dinakantha S. Kumararatne, E. Graham Davies, Adrian J. Thrasher,

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 217 KB

english, 2009

35

Update on the hyper immunoglobulin M syndromes

E. Graham Davies, Adrian J. Thrasher

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

36

Recent advances in the understanding of genetic defects of neutrophil number and function

Gerben Bouma, Phil J. Ancliff, Adrian J. Thrasher, Siobhan O. Burns

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 378 KB

english, 2010

37

Bone morphogenetic protein-4 (BMP4) up regulates key haematopoietic genes in differentiating embryonic stem cells treated with BMP4 short hairpin RNA

Anil Abeyewickreme, Adrian J. Thrasher, Christine Kinnon

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 234 KB

english, 2011

38

Accumulation of the inhibitory receptor EphA4 may prevent regeneration of corticospinal tract axons following lesion

Jez Fabes, Patrick Anderson, Rafael J. Yáñez-Muñoz, Adrian Thrasher, Caroline Brennan, Stephen Bolsover

Journal:

European Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 1.24 MB

english, 2006

39

The future of gene therapy

Cavazzana-Calvo, Marina, Thrasher, Adrian, Mavilio, Fulvio

Journal:

Year:

2004

Language:

english

File:

PDF, 479 KB

english, 2004

40

Gene therapy: Is IL2RG oncogenic in T-cell development?

Pike-Overzet, Karin, de Ridder, Dick, Weerkamp, Floor, Baert, Miranda R. M., Verstegen, Monique M., Brugman, Martijn H., Howe, Steven J., Reinders, Marcel J. T., Thrasher, Adrian J., Wagemaker, Gerard

Journal:

Year:

2006

Language:

english

File:

PDF, 175 KB

english, 2006

41

Gene therapy: X-SCID transgene leukaemogenicity

Thrasher, Adrian J., Gaspar, H. Bobby, Baum, Christopher, Modlich, Ute, Schambach, Axel, Candotti, Fabio, Otsu, Makoto, Sorrentino, Brian, Scobie, Linda, Cameron, Ewan

Journal:

Year:

2006

Language:

english

File:

PDF, 105 KB

english, 2006

42

Out of harm's way

Williams, David A, Thrasher, Adrian J

Journal:

Nature Biotechnology

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

43

RISC control for gene therapy

Qasim, Waseem, Thrasher, Adrian J

Journal:

Nature Biotechnology

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

44

A phagocyte dilemma...

Thrasher, Adrian J, Segal, Anthony W

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 565 KB

english, 2011

45

Wasp in immune-system organization and function

Thrasher, Adrian J.

Journal:

Nature Reviews Immunology

Year:

2002

Language:

english

File:

PDF, 3.59 MB

english, 2002

46

Gene therapy matures in the clinic

Seymour, Leonard W, Thrasher, Adrian J

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 234 KB

english, 2012

47

A Small Molecule Modulator of Prion Protein Increases Human Mesenchymal Stem Cell Lifespan, Ex Vivo Expansion, and Engraftment to Bone Marrow in NOD/SCID Mice

Sindhu T. Mohanty, Claire J. Cairney, Andrew D. Chantry, Sanjeev Madan, James A. Fernandes, Steven J. Howe, Harry D. Moore, Mark J. Thompson, Beining Chen, Adrian Thrasher, W. Nicol Keith, Ilaria Bell

Journal:

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

48

Lack of T-cell responses following autologous tumour lysate pulsed dendritic cell vaccination, in patients with relapsed osteosarcoma

Nourredine Himoudi, Rebecca Wallace, Kathryn L. Parsley, Kimberly Gilmour, Alpha-Umaru Barrie, Karen Howe, Rong Dong, Neil J. Sebire, Antony Michalski, Adrian J. Thrasher, John Anderson

Journal:

Clinical and Translational Oncology

Year:

2012

Language:

english

File:

PDF, 356 KB

english, 2012

49

A functional ISRE is required for myeloid transcription of the p47phox gene

Chloe Marden, Deborah Cunninghame Graham, Adrian Thrasher, Colin Casimir

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2003

Language:

english

File:

PDF, 530 KB

english, 2003

50

Characterisation of Mice with B Cell Specific WASP Deficiency

Mike Recher, Miguel Fuente, Laura Patrizi, Jolan Walter, Siobhan Burns, Adrian Thrasher, Luigi Notarangelo

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

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